Pathophysiology and Pathogenesis of Visceral Fat Obesity
نویسندگان
چکیده
منابع مشابه
Pathophysiology of human visceral obesity: an update.
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic triglyceride storage closely related to clustering cardiometabolic risk factors. Hypertriglyceridemia; increased free fatty acid availability; adipose tissue release of proinflammatory cytokines; liver insulin resista...
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Epidemiological work has shown that visceral adiposity is strongly related to metabolic disorders including insulin resistance. What regulates visceral fat deposition and why it is so metabolically deleterious remains largely unclear. Recent data suggest that the gastrointestinal tract may be a central player in the development of visceral fat accumulation and metabolic syndrome. An impaired gu...
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Introduction. The aim of this study was to investigate the effects of high fat diet-induced obesity and interval and continuous exercise training on visceral fat SIRT1 and insulin resistance in male rats. Method. Forty male rats were divided into two groups: high-fat diet (HFD; n=32) and standard diet (C; n=8). After 10 weeks inducing obesity, eight rats from the HFD and C groups were sacrifi...
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Obesity has become one of the main threats to health worldwide and therefore gained increasing clinical and economic significance as well as scientific attention. General adipose-tissue accumulation in obesity is associated with systemically increased pro-inflammatory mediators and humoral and cellular changes within this compartment. These adipose-tissue changes and their systemic consequences...
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Acute thrombosis may affect the arteries, veins or microvasculature through different pathogenesis and impact a fatal condition. Total thrombosis of coronary artery may cause acute myocardial infarct and in cerebral artery may cause stroke. Relative non fatal conditions refer to deep vein thrombosis in legs or occlusion in microvasculature of the fingers. In the US, coronary artery disease has ...
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ژورنال
عنوان ژورنال: Obesity Research
سال: 1995
ISSN: 1071-7323
DOI: 10.1002/j.1550-8528.1995.tb00462.x